Stercoral colitis mimicking appendicitis
© The Author(s). 2017
Received: 4 January 2017
Accepted: 15 February 2017
Published: 20 February 2017
Stercoral colitis is an inflammatory process involving the colonic wall related to fecal impaction. This rare condition is associated with high morbidity-mortality.
We report a case of a 78-year-old woman with a history of dementia under clozapine who presented a clinical and sonographic presentation of acute appendicitis. The worsening of her clinical condition prompted us to review our diagnosis and modify our approach using the CT scan which was consistent with stercoral colitis. This report concerns an atypical presentation of this condition.
The present case highlights the ability of severe forms of fecal impaction to precipitate very rare and life-threatening complications like stercoral colitis. It also points the importance of including stercoral colitis in the differential diagnosis of acute appendicitis in altered patients under anticholenergic drugs and the critical role of the CT scan as a crucial radiologic adjunct.
KeywordsFecal impaction Stercoral colitis Appendicitis CT scan
A 78-year-old woman with a history of dementia, depression, and hypertension presented to the emergency department with a 3-day history of lethargy and confusion. Among the medications she was taking were clozapine for over 10 years and amlodipine. On examination, she was drowsy, tachycardic (117 beats per minute), and hypotensive (82/42 mmHg) with a temperature of 38 °C. The abdomen was distended with right lower quadrant abdominal pain and active bowel sounds. Rectal examination disclosed a small amount of stool. Blood tests showed raised inflammatory markers with a C-reactive protein of 320 mg/L and a white cell count of 18 × 109/L with normal urea, electrolytes, and liver function tests. Blood gasses showed metabolic acidosis with lactic acid of 4.9.
Ultrasonography abdomen revealed dilated bowel loops with a dilated appendix in a retrocecal position. Broad-spectrum empiric antibiotics were started, and the surgeon was contacted to perform appendectomy.
Fecal impaction (FI) is a common gastrointestinal disorder with potential for major morbidity, especially in the elderly population. Risk factors for this condition include cognitive impairment, cerebral palsy, immobility, rectal hyposensitivity, poor water intake, and use of constipating drugs. Constipation can be a serious side effect of clozapine . The mechanism is most likely the anticholinergic and antiserotonergic effects of the drug.
FI causes increased colonic intraluminal pressure that exceeds the capillary perfusion pressure in the bowel wall  and results in intestinal suffering, an uncommon condition called stercoral colitis. There is a high degree of mortality associated with this disease ranging from 32 to 57% . If left untreated, it may result in a variety of complications, including perforation, peritonitis, and sepsis secondary to bacteremia and absorption of toxins into the blood stream.
CT scan is the modality of choice for diagnosis and shows a thickened rectum impacted with feces, dilated rectosigmoid colon with pericolic fat stranding . In the present case, stercoral colitis mimicked appendicitis in both clinical and sonographic findings. CT scan rectified the diagnosis, which had a great implication regarding the choice of the surgical approach. Management involves prevention of constipation, aggressive fecal disimpaction, and occasionally surgical intervention.
The present case highlights the ability of severe forms of FI to precipitate very rare and life-threatening complications like stercoral colitis. It also points the importance of including stercoral colitis in the differential diagnosis of acute appendicitis in altered patients under anticholenergic drugs and the critical role of the CT scan as a crucial radiologic adjunct.
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Relevant data and supporting material will be available on request.
AE drafted the manuscript under the supervision of MB and CH. All authors critically revised the manuscript and gave their final approval of the version to be published. All authors participated in patient care.
AE is an Anesthesiology Resident physician in the Department of Anesthesiology and Intensive Care at Military Hospital Mohammed V of Rabat.
MB holds an academic rank of Professor, Anesthesiology. He also serves as the Director for Department of Anesthesiology at Military Hospital Mohammed V of Rabat. He is an active researcher in Anesthesiology and Critical Care field.
CH holds an academic rank of Professor, Anesthesiology and Intensive Care. He has published numerous articles in reputed journals. He also serves as the Director for Department of Anesthesiology and Intensive Care at Military Hospital Mohammed V of Rabat.
The authors declare that they have no competing interests.
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Written informed consent was obtained from the family of the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
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- Young CR, Bowers Jr MB, Mazure CM. Management of the adverse effects of clozapine. Schizophr Bull. 1998;24:381–90.View ArticlePubMedGoogle Scholar
- Chakravartty S, Chang A, Nunoo-Mensah J. A systematic review of stercoral perforation. Colorectal Dis. 2013;15:930–5.View ArticlePubMedGoogle Scholar
- Saksonov M, Bachar GN, Morgenstern S. Stercoral colitis: a lethal disease-computed tomographic findings and clinical characteristic. J Comput Assist Tomogr. 2014;38(5):721–6.View ArticlePubMedGoogle Scholar
- Wu CH, Huang CC, Wang LJ, et al. Value of CT in the discrimination of fatal from non-fatal stercoral colitis. Korean J Radiol. 2012;13:283–9.View ArticlePubMedPubMed CentralGoogle Scholar