Bifrontal brain abscesses secondary to orbital cellulitis and sinusitis extension
© The Author(s). 2016
Received: 8 May 2016
Accepted: 28 June 2016
Published: 26 July 2016
Intracranial abscesses are rare and life-threatening conditions that typically originate from direct extension from nearby structures, hematogenous dissemination or following penetrating cerebral trauma or neurosurgery.
A 36-year-old male presented to our emergency department with complaints of left eye swelling, headache and drowsiness. On physical exam, the patient was febrile and his left upper eyelid was markedly swollen with fluctuance and drainage. Maxillofacial computed tomography was obtained to evaluate for orbital pathology but revealed bifrontal brain abscesses.
Brain abscesses should be considered in the differential diagnosis for patients who present with the classic triad of headache, fever and neurological deficit.
KeywordsBrain abscess Emergency medicine Infectious disease Orbital cellulitis Sinusitis
A 36-year-old Hispanic male presented to the emergency department (ED) with complaints of left eye swelling, headache and drowsiness. The patient had been seen two weeks prior to this visit at another emergency department for left eye swelling. At that time, he was diagnosed with a periorbital abscess and discharged home from the ED on a course of oral antibiotics. Over the following two weeks, the patient’s symptoms progressed to headache and increasing lethargy. The patient now also reported worsening left upper eyelid swelling with discharge and painful range of motion of the left globe. He reported no vision changes. In the ED, the patient was febrile, temperature was 102 °F. The left upper eyelid was swollen, erythematous, and fluctuant with pointing and purulent yellowish discharge. Visual acuity was 20/20 in both eyes. There were no focal motor or sensory deficits on exam. However, the patient did exhibit mental status changes including indifference to his current condition and a flat affect which was inconsistent with his baseline.
Bifrontal brain abscesses
Brain abscesses are focal pyogenic intracerebal infections which may present as life-threatening emergencies . Infections can occur within the brain by direct extension from nearby structures, hematogenous dissemination or following penetrating cerebral trauma or neurosurgery . Immunocompromised hosts are at particular risk, with etiologies in these patients commonly secondary to amebic or fungal infection. The classic triad for the clinical presentation of brain abscess includes headache, fever and focal neurological deficit, although the whole triad is seen in less than 50 % of cases . This patient’s presentation with flat affect interestingly coincides with the psychopathology of the abscess location in the frontal lobes. Diagnosis is made by imaging studies including CT and MRI but is sometimes seen on radionuclide scans. Typically, images will reveal a ring-enhancing lesion with variable surrounding edema . Treatment of brain abscesses requires a combination of drainage and antimicrobial therapy. Until gram stain results are available, antibiotic regimens should be based on the presumptive source of the infection.
ED, emergency department; I&D, Incision and drainage; CT, computed tomography; MRI, magnetic resonance imaging
DT drafted the manuscript. AR treated the patient and revised the manuscript. SH helped to draft the manuscript and revised it. All authors read and approved the final manuscript.
DT is a third year Emergency Medicine resident physician at St. Joseph’s Regional Medical Center. AR is an attending physician in the Department of Emergency Medicine at St. Joseph’s Regional Medical Center. SH is an attending physician and faculty in the Department of Emergency Medicine at St. Joseph’s Regional Medical Center and New York Medical College.
The authors declare that they have no competing interests.
Consent for publication
Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.
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